LISA CLARK: If you have any of the symptoms, you should let your doctor know, of course -- any of the major symptoms for kidney disease. Maybe we should just hit those really quickly. They include frequency of urination, change in frequency of urination?
LEONARD STERN, MD: Frequency of urination might be a symptom of a urinary tract infection, and many people get urinary tract infections. It's very common in women, very common in older men with prostate disease, not necessarily a cause of kidney failure or an acute symptom related to an illness.
JAI RADHAKRISHNAN, MD: It should lead one to seek advice from a practitioner, because it could well harbor a kidney problem.
LISA CLARK: What other source of things might a patient notice about their physical situation that changes?
JAI RADHAKRISHNAN, MD: If a person feels perfectly and suddenly feels run down, tired, weak, they should definitely seek help from a practitioner. Kidney failure could be the cause for all this. If there's pain in the flanks where the kidneys are, if you have pain down there and it's recurrent and disabling, especially, you should definitely get seen, because there could be a stone sitting there, causing progressive kidney damage. If you have a burning of the urine, if you feel scratching in the skin, these are some of the signs, or you've lost your appetite just out of the blue, for no reason, or you're not able to concentrate, your mind's wandering. All these could say that you could have pretty severe kidney disease that needs to be looked at.